Ten people, including two firefighters, were treated at the scene or transported to area hospitals with non-life-threatening injuries.
While en route, dispatch advised incoming units that they had multiple callers reporting heavy smoke from the building.
One firefighter was injured during a fire involving hoarding conditions in Worcester.
The hosebed carries 2,600 feet of large-diameter hose, the same that FDNY satellite units respond with. The top of the vehicle has a large Williams electric deluge gun with two smaller TFT guns on the rear of the unit and a 1,000-gallon Class A foam tank.